Many people begin to notice droopy or heavy eyelids as they get older. The upper eyelids can slowly start to sit lower, making the eyes look tired, hooded, or less open than they once were. This condition is called acquired ptosis, and it is very common with aging.
Upneeq is a prescription eye drop designed to temporarily lift low-lying eyelids without surgery. By gently raising the eyelid, it can make the eyes appear more open, brighter, and more refreshed.
UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution, 0.1%) is a prescription eye drop used to treat low-lying lids (acquired blepharoptosis) in adults. Like Latisse, Upneeq is only available with a prescription from a medical provider.
Upneeq works by stimulating Müller’s muscle, one of the muscles responsible for lifting the upper eyelid. This muscle is involuntary, meaning you cannot control it consciously.
When the medication activates this muscle, the eyelid lifts slightly, allowing more of the eye to be visible. This can make the eyes appear more open, awake, and youthful.
Upneeq offers a simple, non-surgical way to improve the appearance of drooping eyelids.
• Helps lift low-lying eyelids for a more open appearance
• Can brighten the eyes and reduce the look of heaviness or fatigue
• Effects typically last around 6–8 hours
• Can be used daily or only when desired, similar to using makeup for the eyes

• Lifts the eyelids quickly
• Many patients notice improvement within 30 minutes
• Some patients may see effects in as little as 5 minutes
In clinical studies:
• 84% of patients experienced some level of improvement
• 74% experienced more than a 50% improvement in eyelid lift
In one study, some patients saw a lift in their eyelids as fast as 5 minutes after the first dose
Many people find the drops take effect within a few minutes. The vast majority of people who try upneeq see results within 30 minutes. Occasionally it can take up to 2 hours to take effect to enhance your eyes. We find that as long as the drop landed in the eye and not on the lid, the effect is very rapid.
Upneeq is a prescription medication. Questions? We are happy to help.
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