How Regenerative Medicine Is Reversing Aging: A Longevity Deep Dive with Dr. Richard Baxter 

Published on: August 29, 2025

What if we could turn back the biological clock? 

On this episode of Medspa Mayhem, Dr. Kate Dee sits down with board-certified plastic surgeon Dr. Richard Baxter to discuss regenerative medicine for aging, evidence-backed longevity treatments, and what’s actually working to improve both how we look—and how long we stay healthy. 

“What’s most exciting is that there are things you can do, shown in prospective clinical trials, that reverse aging.” – Dr. Richard Baxter 

What Is Regenerative Medicine for Anti-Aging? 

Regenerative medicine focuses on restoring and rejuvenating tissue at a cellular level, going beyond superficial cosmetic treatments to actually target the root causes of aging. It includes a range of therapies designed to: 

  • Boost collagen and elastin production 
  • Repair damaged skin and tissue 
  • Stimulate cellular renewal and metabolic health 

In aesthetics, this often looks like PRP, exosomes, nanofat injections, and new biologic solutions like PDGF (platelet-derived growth factor)

Cutting-Edge Aesthetic Tools: PRP, PDGF, and Beyond 

Dr. Baxter shares how his practice has evolved beyond traditional facelifts to include regenerative tools like: 

  • PRP (Platelet-Rich Plasma): Uses your own blood to deliver growth factors to aging or damaged tissue. 
  • PDGF / Ariessence: A potent, injectable version of platelet-derived growth factor—no blood draw required, and more targeted results. 
  • Exosomes: Membrane-bound vessicles loaded with signaling molecules for healing and regeneration. 
  • Nanofat: Fat injections without the fat cells—just the growth factors—used for facial rejuvenation. 

“We’re not just reshaping tissue—we’re restoring it.” 

Biological Age vs. Chronological Age 

One of the most powerful shifts in longevity medicine is the ability to measure biological age using epigenetic testing. These tests look at DNA methylation markers to determine how your body is aging on a cellular level—and how interventions are working over time. 

This gives patients and providers an objective way to track the impact of supplements, peptides, and lifestyle changes. 

Therapies That May Reverse Aging 

Therapeutic Plasma Exchange 

A groundbreaking procedure that filters the plasma in your blood and replaces it with clean proteins. In clinical trials, this has reversed aging biomarkers—making it the first interventional treatment proven to do so in a randomized, controlled trial. 

“Right now, plasma exchange is the only intervention shown in a clinical trial to reverse biological age.” 

Metformin 

Originally a diabetes drug, metformin has shown longevity benefits in multiple studies—including reduced cancer risk and longer lifespan even in diabetic patients. 

Peptides 

Peptides like growth hormone-releasing peptides aim to replicate the benefits of HGH without the side effects. When used correctly, they can promote better metabolism, energy, and recovery. 

Everyday Longevity: Lifestyle + Supplements 

Dr. Baxter emphasizes that while advanced treatments are exciting, the foundations of healthy aging start with daily habits

  • Intermittent fasting (eating within an 8-hour window) 
  • Consistent exercise 
  • Sleep hygiene 
  • Sun protection 
  • Smoking cessation 
  • And a few low-risk supplements show promise too: 
  • Alpha-ketoglutarate (AKG) – may reverse aging biomarkers 
  • NAD+ precursors – support cellular energy and repair 

How to Find Safe, Qualified Providers 

As treatments like plasma exchange and biologic injections become more accessible, Dr. Dee and Dr. Baxter caution listeners to prioritize provider safety and training

“You can’t go to some random provider for this. You need someone highly trained and trustworthy.” 

Start Your Longevity Journey 

Whether you're looking to improve your skin, increase energy, or extend your healthspan, regenerative medicine for aging is no longer science fiction—it’s here, and it’s evolving fast. 

🎧 Listen to the full episode: Medspa Mayhem Podcast 
📥 Download Dr. Baxter’s free longevity guide: drbaxter.com/resources 
📍 Dr. Baxter’s Clinic: Mountlake Terrace, WA  

Ready to explore anti-aging and regenerative treatments? 

Book a consultation to start your personalized longevity plan today. 

Author Profile Picture
Dr. Kate Dee grew up in New York City and attended Yale for college and medical school, finishing her MD in 1994. She first came to Seattle for residency at the University of Washington in 1995 followed by fellowship in Breast Imaging at the University of California, San Francisco. She was a breast cancer specialist at Seattle Breast Center for 13 years, receiving Top Doc honors each year since 2010. After a successful career in breast cancer, Kate found her way to aesthetic medicine in her 40's when her expertise with needle procedures coincided with a deep interest in anti-aging techniques. Kate lives in West Seattle with her 3 teens. She especially loves to ski, cycle, play tennis and pickle ball.
Learn More About Dr. Dee
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