Anti-Aging Ingredients: Retinol & Retinoic Acid

Published on: July 28, 2015

by Kate Dee, MD

Retinol and Retinoic Acid are both forms of Vitamin A, the most important and effective of the anti-aging ingredients. Retinol is a topical Vitamin A that must be taken into the cell and converted to the active form retinoic acid inside the cell to have its effect. Retinoic Acid (Retin-A/Tretinoin) is the active form of the vitamin. Retinols are beneficial cell-communicating ingredients and antioxidants, helping skin cells become healthier by increasing the amount of skin support substances. Retinols increase the skin’s collagen production and slow its breakdown, resulting in firmer skin with an improved texture and enhanced barrier function. Retinol also lightens brown spots caused by sun exposure. Retinols also trigger more rapid epidermal cell turnover and exfoliation, making way for new cell growth beneath the surface.

Retinols are available in over-the-counter topicals in the forms of retinol, retinyl palmitate, and retinaldehyde. Retin-A is available by prescription only. It should be strongly considered by those who desire to keep their skin in top shape through the years.

The labeling of Retinol products is not regulated-- stay away from the retinol products at the beauty counter at the department stores-- they can label the product as containing retinol when there is only a trace ineffective dose. Retinol should be at least 1% concentration to be absorbed by your skin cells-- don't waste your money!

Retinols often cause redness and flaking, especially in the beginning of use. Some may need to start at a lower dose or less frequent application and advance to daily use over time.

Author Profile Picture
Dr. Kate Dee grew up in New York City and attended Yale for college and medical school, finishing her MD in 1994. She first came to Seattle for residency at the University of Washington in 1995 followed by fellowship in Breast Imaging at the University of California, San Francisco. She was a breast cancer specialist at Seattle Breast Center for 13 years, receiving Top Doc honors each year since 2010. After a successful career in breast cancer, Kate found her way to aesthetic medicine in her 40's when her expertise with needle procedures coincided with a deep interest in anti-aging techniques. Kate lives in West Seattle with her 3 teens. She especially loves to ski, cycle, play tennis and pickle ball.
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